Histamine dihydrochloride. The Effective Active.
As a medicinal pain therapy cream, we were the first to use Histamine dihydrochloride and moisture binding hydration in a topical pain relief formula. Histamine dihydrochloride is an FDA-approved, over-the-counter drug working as an effective pain blocker, preventing pain signaling neurons from getting to the brain, thus, acting as a “positive interference” against pain. Additionally, Histamine dihydrochloride, when applied topically, causes vasodilation at the site of application allowing for more blood to reach the site, enabling the body to heal and relieve pain in a more effective, natural way.